Deutsches MDS-Forum - Dresden 2006: Vom Nihilismus zum Algorithmus
Molekulare Targets für die Therapie myelodysplastischer Syndrome
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Ben-Yehuda D, Krichevsky S, Caspi O.
Microsatellite instability and p53 mutations in therapy-related leukemia suggest mutator phenotype.
Blood 1996;88:4296-4303. PM:8943866
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Tasak T, Lee S, Spira S.
Infrequent microsatellite instability during the evolution of myelodysplastic syndrome to acute myelocytic leukemia.
Leuk Res 1996;20:113-117. PM:8628009
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Krug U, Ganser A, Koeffler HP.
Tumor suppressor genes in normal and malignant hematopoiesis.
Oncogene 2002;21:3475-3495. PM:12032783
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Chen Z, Sandberg AA.
Molecular cytogenetic aspects of hematological malignancies: clinical implications.
Am J Med Genet. 2002;115:130-141. PM:12407693
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Hirai H.
Molecular pathogenesis of MDS.
Int J Hematol. 2002;76:213-221. PM:12430928
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Greenberg P, Cox C, LeBeau MM.
International scoring system for evaluating prognosis in myelodysplastic syndromes.
Blood 1997;89:2079-2088. PM:9058730
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Fenaux P.
Chromosome and molecular abnormalities in myelodysplastic syndromes.
Int J Hematol 2001;73:429-437. PM:11503956
[Medline]
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Pabst T, Mueller BU, Zhang P.
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.
Nat Genet 2001;27:263-270. PM:11242107
[Medline]
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Gombart AF, Hofmann WK, Kawano S.
Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias.
Blood 2002;99:1332-1340. PM:11830484
[Medline]
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Hofmann WK, Miller CW, Tsukasaki K.
Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias.
Leuk Res. 2001;25:333-338. PM:11248330
[Medline]
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Herman JG, Baylin SB.
Gene silencing in cancer in association with promoter hypermethylation.
N Engl J Med 2003;349:2042-2054. PM:14627790
[Medline]
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Quesnel B, Guillerm G, Vereecque R.
Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression.
Blood 1998;91:2985-2990. PM:9531610
[Medline]
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Hofmann WK, de Vos S, Komor M.
Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow.
Blood 2002;100:3553-3560. PM:12411319
[Medline]
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Lee YT, Miller LD, Gubin AN.
Transcription patterning of uncoupled proliferation and differentiation in myelodysplastic bone marrow with erythroid-focused arrays.
Blood 2001;98:1914-1921. PM:11535529
[Medline]
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Ueda M, Ota J, Yamashita Y.
DNA microarray analysis of stage progression mechanism in myelodysplastic syndrome. Br J Haematol 2003;123:288-296. PM:14531911
[Medline]
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